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Long Acting Reversible Contraception

MedxLife

This category includes contraception devices which have long duration of action and fertility can be regained at any point of time by its expulsion from the body.

These includes:
• Injectable DMPA
• Progesterone Implants
• Intrauterine devices – CuT
• MIRENA


Injectable DMPA:

• It is available under the name DEPO – PROVERA.
• DMPA stands for Depo Medroxy Progesterone Acetate.
• It is made available free of cost by the government of India.
• It can be used freely by breastfeeding mother also after 6 weeks post partum as it only contains progesterone.
• A dose containing 150 mg is injected every 3 monthly intramuscularly.
• It is contraception of choice in:
– Females with epilepsy as it decreases seizures.
– Females with scikle cell anemia as DMPA decreases sickling crisis.
• Some adverse effects associated with it are:
– Bone loss
– Irregular vaginal bleeding
– Delay in return of fertility after stopping the method (about 12 months)

Progesterone Implants:

• It contains 6 Silastic rods containing Levonorgestral.
• It is a Norplant system.
• It acts by inhibiting ovulation, cervical mucus thickening, altered tubal motility and makes endometrium thin (all these actions are due to progesterone in it).
• Failure rate is 0.05%
• Return to fertility after implant withdrawal is quick unlike that of injectable DMPA.
IMPLANON
• Latest type of progesterone implants.
• It consists of only one rod containing 68 mg of etonorgestral.
• It is inserted subdermally in medial aspect of non dominant arm.
• It is effective for 3 years.
• It is most effective method with failure rate of 0.01%.
NEXPLANON
• Same as IMPLANON
• It is radio opaque

CAPRANON

• It is biodegradable type of implant, i.e., its removal is not required (gets destroyed in the body itself by the action of enzymes after a certain period of time).
• It is effective for 12 months.

Intrauterine Devices:

Intrauterine devices (IUD) or intrauterine contraceptive devices (IUCD) are the devices which are inserted in the uterine cavity in order to control pregnancy.
Intrauterine devices are as follows:
1. Lippes Loop – these are large loops which are now no longer in use.
2. Copper containing – CuT, Multiload
3. Hormone releasing – Progestasert, MIRENA

CuT 380 A:

• It is available by the government of India free of cost.
• It has a life span of 10 years.
• It may sometimes be used as a method of emergency contraception.
• Copper decreases sperm motility and viability hence helps in inhibition of fertilization. It also inhibits implantation by initiating local inflammatory response in the endometrium.

Contraindications of CuT are-
– Post septic abortion
– Anatomical uterine abnormalities (eg -septate uterus)
– Active genital tract infection
– Current PID
– Puerperal sepsis
– Genital tract malignancy
– Unexplained vaginal bleeding
– Prolonged labor

Timing of insertion of CuT-
– Post partum (within 48 hrs of delivery)
– Immediately after delivery of placenta
– After cesarean section
– Post abortal
– Interval insertion (within first 5 days of menstrual cycle otherwise other contraception method needed for that month)

Adverse effects of CuT-
– Increased mentrual bleeding
– Increased pelvic pain
– May cause actinomycosis infection
– May cause perforation of membranes
– Expulsion of CuT which may not be noticed.

MIRENA:

• This method is effective for 5 years.
• It contains 52 mg levonorgestral
• It can be used in hormone replacement therapy (for progesterone)
• It’s main mechanism of action is by inhibiting implantation.
• It lowers the risk of PID.
• It also lowers the blood loss which is helpful in abnormal uterine bleeding (endometriosis, fibroids)
• It has a local effect, therefore it causes no systemic adverse effects.
• It is not a method of emergency contraception.

Contributor- Medico Eshika Keshari

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